Real work-at-home jobs do exist but you have to have an arrangement with an organization set up to do business that way and most often they require special skills like computer programming, managing a website or typing. Businesses like contractors and subcontractors that don't have a walk-in office often have their telephones answered and their purchasing and bookeeping done by someone at home.
The answer depends on where you are, what skills you have and your ability to make the connection with such an organization.